Should women use sildenafil to reduce their risk of Alzheimer’s disease? Elizabeth Tracey reports
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- Sildenafil is often known by the brand name Viagra, primarily for men.
- Researchers are exploring other PDE5 inhibitors for women’s sexual health.
- Efficacy of sildenafil in women might depend on underlying health conditions.
- Women with cardiovascular issues should be particularly cautious with sildenafil.
- Some women report increased sexual satisfaction after using sildenafil.
- Medical advice is crucial before women consider sildenafil as a treatment.
Archived from the original (PDF) on 10 September 2011. "Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules". ^ a b Webb DJ, Freestone S, Allen MJ, Muirhead GJ (March 1999). "Sildenafil citrate and blood-pressure-lowering drugs: results of drug interaction studies with an organic nitrate and a calcium antagonist".
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"Strategies for managing sexual dysfunction induced by antidepressant medication". The Cochrane Database of Systematic Reviews (5) CD003382. Archived from the original on 10 October 2020. "Efficacy and safety of sildenafil treatment in pulmonary arterial hypertension: a systematic review". Archived from the original on 29 August 2021.
What should I know about storage and disposal of sildenafil?
"Raynaud's phenomenon and digital ischaemia--pharmacologic approach and alternative treatment options". "Efficacy of Sildenafil on healthy humans in high‑altitude hypoxia at rest and during exercise: A meta‑analysis". "Interventions for preventing high altitude illness: Part 1. Archived from the original on 10 June 2017. ^ "FDA Updates Labeling for Viagra, Cialis and Levitra for Rare Post-Marketing Reports of Eye Problems" (Press release). ^ Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA (May 1998). "Oral sildenafil in the treatment of erectile dysfunction. Archived from the original on 14 January 2012. "Onset and duration of action of sildenafil for the treatment of erectile dysfunction". ^ "Scientist who developed Viagra receives knighthood in New Year's Honours". Archived from the original on 14 January 2023. "Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond". Archived from the original on 26 September 2008. Our clinicians regularly offer patients the opportunity to take part in trials of new drugs and treatments. Morriston Hospital in Swansea, was the first in the world to trial Viagra! ^ Boolell M, Allen MJ, Ballard SA, Gepi-Attee S, Muirhead GJ, Naylor AM, et al. "Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction". "Sildenafil (Viagra), a potent and selective inhibitor of Type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction". "Drug repositioning: identifying and developing new uses for existing drugs". Archived from the original on 22 April 2019.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Kamagra | 100mg | 32 Pills | 121.24€ 115.47€ | |
| Viagra Generic | 200mg | 120 + 8 Pills | 204.80€ 195.05€ | |
| Viagra Generic | 25mg | 270 + 8 Pills | 184.26€ 175.49€ | |
| Kamagra Oral Jelly | 100mg | 10 Sachets | 54.55€ 51.95€ | |
| Viagra Generic | 100mg | 90 + 6 Pills | 129.02€ 122.88€ | |
| Viagra Generic | 25mg | 360 + 10 Pills | 213.68€ 203.50€ | |
| Viagra Generic | 25mg | 120 + 6 Pills | 125.56€ 119.58€ | |
| Viagra Generic | 100mg | 180 + 8 Pills | 199.37€ 189.88€ | |
| Viagra Generic | 200mg | 60 + 4 Pills | 125.19€ 119.23€ | |
| Viagra Generic | 150mg | 270 + 10 Pills | 326.61€ 311.06€ | |
| Kamagra Polo | 100mg | 84 + 4 Pills | 244.49€ 232.85€ | |
| Viagra Generic | 25mg | 20 Pills | 37.74€ 35.94€ |
Archived from the original on 10 June 2019. "Health situation in former communist bloc is dire, says Unicef". Archived from the original on 1 November 2012. ^ Gurevich M, Cormier N, sildenafil 60mg Leedham U, Brown-Bowers A (August 2018). Sexuopharmaceutical use by men as prevention and proficiency". "Spreading the Word, but What Word is That? Viagra and Male Sexuality in Popular Culture". "A new view of women's sexual problems: Why new? Archived from the original on 3 January 2009. Archived from the original on 12 October 2008. "Sales of Impotence Drugs Fall, Defying Expectations". Archived from the original on 11 October 2007. ^ "Pfizer Courting More Controversy with Viagra 'Advergaming'". Archived from the original on 19 December 2019. Archived from the original on 6 May 2018. Archived from the original on 9 January 2009. Archived from the original on 22 February 2021. ^ a b "Viagra now available over the counter without prescription in the UK". Archived from the original on 26 March 2021.
Author information
U.S. Food and Drug Administration (FDA). Archived from the original on 31 March 2021. Archived from the original on 12 August 2025. ^ "Sildenafil Drug Usage Statistics, United States, 2014 - 2023".
Can Viagra make a woman wet?
"Generic Viagra: Two versions of sildenafil hit the market today". Archived from the original on 25 November 2018. Archived from the original on 12 February 2022. "With Viagra Now Available Over-The-Counter In The U.K., Will The U.S. "Phosphodiesterase inhibitors for erectile dysfunction in patients with diabetes mellitus". Archived from the original on 8 December 2013. "The coming generics threat to Pfizer's Viagra brand just got scarier".
- Awareness of sildenafil's potential side effects helps women make informed choices.
- Women should avoid using sildenafil with nitrates to prevent dangerous drops in blood pressure.
- Proper diagnosis of sexual dysfunction can guide appropriate treatment options.
- Scientific research continues to explore safer, women-specific sexual health drugs.
- Sildenafil’s long-term effects on women are not yet fully understood.
- Healthcare providers can help determine if sildenafil is appropriate for individual cases.
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Efficacy of Sildenafil Citrate on Female Sexual Dysfunction in A Sample of Egyptian Females, A Prospective Placebo Controlled Study
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Study Design
Use of sildenafil (Viagra) in patients with cardiovascular disease. American College of Cardiology/American Heart Association". Journal of the American College of Cardiology. ^ "Viagra (Sildenafil Citrate): Side Effects, Interactions, Warning, Dosage & Uses". Archived from the original on 12 July 2018. Archived from the original on 7 December 2017. "Pfizer to lose patent of drug Viagra, Indian companies gear up with copycat versions: Pfizer's patent for the formulation of Viagra, used to treat impotence in men, ends in the US in 2020". Archived from the original on 17 April 2021. ^ "Set to conquer US, Indian 'Viagras' may give Pfizer a hard Time". Archived from the original on 22 December 2020. ^ a b "Pfizer Settles Viagra® Patent Litigation With Teva". "Lockout Supplements Issues Voluntary Nationwide Recall of Boner Bears Chocolate Syrup Due to Undeclared Sildenafil". Archived from the original on 19 November 2016.
What special dietary instructions should I follow?
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Vyleesi (bremelanotide)
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| Country | Legal Status | Prescription Required | Notes |
|---|---|---|---|
| USA | Approved for certain uses | Yes | Off-label for women often not approved |
| UK | Prescription-only | Yes | Approved for male ED; off-label use in women |
| Canada | Restricted use | Yes | Prescription required; variable by province |
| Australia | Prescription-only | Yes | Limited clinical guidelines for women |
{{cite web}}: CS1 maint: deprecated archival service (link) ^ Teva Canada Ltd. v. Pfizer Canada Inc., 2012 SCC 60 at par. "Supreme Court ruling could lead to cheaper versions of Viagra". Archived from the original on 10 March 2013. "Canadian Supreme court rules Viagra patent invalid". Archived from the original on 11 November 2012.
Adverse effects
"Young men add Viagra to their drug arsenal". Archived from the original on 4 September 2014. "Recreational use and misuse of phosphodiesterase 5 inhibitors". Archived from the original on 21 August 2016. "Sildenafil does not improve sexual function in men without erectile dysfunction but does reduce the postorgasmic refractory time". ^ "Viagra patent tossed out by Supreme Court: Decision allows generic versions of drug to be produced". Archived from the original on 18 September 2013. ^ "Pfizer Canada drops Viagra price after generic versions get Supreme Court green light".
| Side Effect | Severity | Frequency | Management Tips |
|---|---|---|---|
| Headache | Mild to moderate | Frequent | Hydration, pain relievers |
| Flushing | Mild | Common | Cooling measures |
| Nasal Congestion | Mild | Occasional | Decongestants |
| Dizziness | Mild | Less common | Sitting or lying down |
| Visual Disturbances | Rare | Rare | Seek medical attention |
Archived from the original on 30 November 2012. Archived from the original on 27 December 2013.
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